Making synthetic analogs and redesigning the gecko skin micro/nanoarchitecture and apply it to biofilm reduction in all places providing healthcare and treatments. For instance, in the surgical operating theatre, in hospital wards, the clinic, dental and doctor practices, coating surfaces where there are high rates of transmission between people. Surfaces of that nature include door handles, light switches, etc. The Gecko texture is particularly effective against gram-negative strains of bacteria. These are bacteria with comparatively thin cell walls and, as a result, get easily punctured by the Gecko spinules. In general, a majority of disease-causing bacteria are of this type. The coating texture directs against antibiotic-resistant bacteria, which are a significant threat to human health.